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the PLUG

GROUP

Pleural Pressure Working Group

PROMOTING MONITORING IN RESPIRATORY FAILURE

Pen and ink drawing of Antoine Lavoisier performing a respiration experiment while his wife takes note

PUBLIC DOMAIN

 

WHO

WE ARE

MEETINGS

Upcoming meetings...

PLUG MEETING in TORONTO

WHEN

November 11th, 2019 from 12:00 to 13:30

WHERE

Critical Care Canada Forum (CCCF) - criticalcarecanada.com

Sheraton Hotel - York Room

WHAT

Welcome and introduction. L Brochard

 

Discussion of new studies & ongoing projects

  • End-inspiratory hold during PSV. A validation study. Protocol and preliminary results (Alice Grassi)

  • The ICEBERG study (Giacomo Bellani)

  • Pmus during Reverse triggering (Irene Telias)

  • Update on the Lung and Diaphragm Protective Ventilation meeting and manuscript (Ewan Goligher)

Past meetings

 

2019 ESICM LIVES Meeting

Berlin, Germany

30th September 2019 at 18:00-20h00

29th ARGENTINIAN MEETING OF INTENSIVE CARE MEDICINE - https://congresos.sati.org.ar

Mendoza, Argentina

4th-6th September 2019

41st ANNUAL MEETING OF THE JAPANESE SOCIETY FOR RESPIRATORY CARE 

http://jsrcm41.jp/index.html#

Osaka, Japan

3rd-4th August 2019

LUNG and DIAPHRAGM-PROTECTIVE

VENTILATION CONSENSUS CONFERENCE

MiCo Milano, Milan, Italy

6th-8th May 2019

Members of the Pleural Pressure Working Group gathered from around the world for a state-of-the-art meeting on an important new challenge in the management of patients with acute respiratory failure: integrating the traditional focus on lung-protective ventilation with the emerging paradigm of diaphragm-protective mechanical ventilation. The meeting involved two days of extensive discussion and debate about the best available mechanistic and clinical evidence supporting various facets of lung and diaphragm-protective ventilation strategies. Over the two days, a genuine consensus emerged over the importance of addressing the new issues raised and the need for advances in monitoring and intervention to target mechanisms of lung and diaphragm injury during ventilation. The writing committee is now tasked with summarizing the discussion and developing various position statements to be evaluated by the larger group. Participants agreed that the meeting was a great success; in particular, it was a phenomenal opportunity for junior investigators in the field to interact with more established leaders. The importance of this meeting for clinical practice and for research in the field will emerge over years to come.

ESICM Paris Meeting 2018
 
 

RESEARCH

Incidence of dyssynchronous spontaneous Breathing Effort, breath-stacking and reverse triggering in early ARDS -

The BEARDS project -

Objectives

  1. To describe the incidence of spontaneous breathing efforts, reverse triggering, breath stacking and short cycles, as well as other asynchronies like wasted efforts in the first week of ARDS and AHRF.

  2. To analyze the presence of main dyssynchronies with its corresponding changes in transpulmonary pressure swings, plateau pressure and volume delivered by the ventilator in those breaths, and quantify the breathing efforts generated.

  3. To associate the incidence of dyssynchronies (including reverse triggering) during the early phase of ARDS and AHRF, with outcome (ventilator free days, intensive care unit (ICU) stay, mortality, pneumothorax as secondary outcome).

  4. To understand the relationship between sedation levels and regimens and the different types of dyssynchronies.

Current status

Recruiting

Principal investigator

Laurent Brochard

email: brochardl@smh.ca

Link to clinicaltrials.gov

PRessure suppOrT vEntilation + Sigh in aCuTe hypoxemIc respiratOry failure patieNts (PROTECTION): a pilot randomized controlled trial 

Objective

This pilot RCT will serve to test the hypothesis that application of PSV+Sigh in spontaneously breathing intubated patients with mild to moderate AHRF and ARDS is feasible and to collect preliminary data on the safety of such an approach.

Current status

Recruiting

Principal investigators

Tommaso Mauri (email: tommaso.mauri@unimi.it)

Laurent Brochard (email: brochardl@smh.ca)

Link to clinicaltrials.gov

  

 

VIDEOS

01. How to measure driving and transpulmonary driving pressure

03. How to inflate the esophageal balloon

05. How to insert the esophageal balloon

07. How to measure

PEEPi

02. How to recruit the lung with transpulmonary pressure

04. The different pressure in the thorax

06. How to calculate

WOB & PTP

08. How to set PEEP

using transpulmonary pressure

09. How to measure

transpulmonary pressure

in a passive patient

Work in progress...  more videos to come

 

Click on "YOUR STORIES - The PLUG" button and you will be able to ask question, post comments, upload interesting cases you want to share with the PLUG community. 

YOUR STORIES

OUR BLOG

 

RESOURCES

& PUBLICATIONS

Interested in publications or websites that may assist in the management and monitoring of patients with respiratory failure? Click on the icons below!

PUBLICATIONS
ONLINE RESOURCES

Do you have any recommendation for a publication or a website you think we should add to the list? Email us at: plug.workinggroup@gmail.com

 

EVENTS

The PLUG group meets regularly during international intensive care medicine conferences.

NUMBERS

 
 

GET IN

TOUCH

We can't wait to hear from you: